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3Novices: Big Data About Key Protein Reveal Genetic Clues in Humans

After analysing big data about a key protein at Washington University in St. Louis, computer scientists have discovered its connection in human history as well as clues about its role in complex neurological diseases. Through a novel method, Sharlee Climer and Weixiong Zhang discovered a region encompassing the gephyrin protein - master regulator of receptors in the brain that transmit messages - on chromosome 14 that underwent rapid evolution after splitting in ...



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