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3Novices: Molecular Link Between Obesity and Type 2 Diabetes

Researchers at University of California have revealed that obesity causes inflammation and the inflammatory molecule LTB4 promotes insulin resistance, a first step in developing type 2 diabetes. They found that genetically removing the cell receptor that responds to LTB4, or blocking it with a drug, improves insulin sensitivity in obese mice. Senior author Jerrold M. Olefsky said, "This study is important because it reveals a root cause of type 2 diabetes and now ...



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